Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPR183 | P32249 | 5/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365524 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53SMN1; SMN2HSD11B1 | |
| SCHEMBL9366744 | 0.91 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2RAB9AKMT2AGPR183 | |
| SCHEMBL9366747 | 0.91 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2RAB9AKMT2AGPR183 | |
| SCHEMBL9366552 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNATP53SMN1; SMN2HSD11B1 | |
| SCHEMBL9366555 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNATP53SMN1; SMN2HSD11B1 | |
| SCHEMBL9366481 | 0.75 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9366567 | 0.75 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9366482 | 0.75 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9365679 | 0.75 | LMNA (0.53) | ALDH1A1LMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9365675 | 0.75 | LMNA (0.53) | ALDH1A1LMNASMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |