SCHEMBL936554

SCHEMBL936554

C#CCCC=CCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.39
TRPV1 Q8NER1 2/20 0.39
F7 P08709 2/20 0.39
F3 P13726 2/20 0.39
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TERT O14746 3/20 0.34
CYP1A2 P05177 2/20 0.34
MAPT P10636 2/20 0.34
CYP2C19 P33261 2/20 0.34
BLM P54132 2/20 0.34
HSD17B10 Q99714 2/20 0.34
FABP4 P15090 2/20 0.34
PTPN1 P18031 2/20 0.34
PPARG P37231 2/20 0.34
KMT2A Q03164 2/20 0.34
PPARD Q03181 2/20 0.34
PPARA Q07869 2/20 0.34
GMNN O75496 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL936553 1.00 FAAH (0.39) FAAHTRPV1F7F3TSHR
SCHEMBL17965772 0.98 FAAH (0.38) FAAHTRPV1F7F3TSHR
SCHEMBL17965771 0.98 FAAH (0.38) FAAHTRPV1F7F3TSHR
SCHEMBL9728293 0.93 FAAH (0.48) FAAHTRPV1F7F3TERT
SCHEMBL21670611 0.91 FAAH (0.52) FAAHTRPV1F7F3TERT
SCHEMBL21670602 0.91 FAAH (0.52) FAAHTRPV1F7F3TERT
SCHEMBL21670610 0.91 FAAH (0.52) FAAHTRPV1F7F3TERT
SCHEMBL17965693 0.88 TRPV1 (0.34) FAAHTRPV1
SCHEMBL17965695 0.88 TRPV1 (0.34) FAAHTRPV1
SCHEMBL17965720 0.87 TRPV1 (0.53) FAAHTRPV1F7F3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818523-B Process for preparing 5-en-1-ynes and compounds derived therefrom 信越化学工业株式会社 2023-05-02 CN disclosed
EP-3608302-B1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND SHINETSU CHEMICAL CO (JP) 2021-10-20 EP disclosed
CN-105859529-B Method for producing asymmetric conjugated diyne compound and method for producing Z, Z-conjugated diene compound using the same 信越化学工业株式会社 2020-10-16 CN disclosed
US-10781146-B2 Process for preparing a 5-alken-1-yne compound, (6Z)-1,1-dialkoxy-6-nonen-2-yne compound, (2E,6Z)-2,6-nonadienal and (2E)-cis-6,7-epoxy-2-nonenal, and 1,1-dialkoxy-6-nonen-2-yne compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-09-22 US disclosed
CN-110818523-A Process for preparing 5-en-1-ynes and their derivatives and 1, 1-dialkoxy-6-nonene-2-ynes 信越化学工业株式会社 2020-02-21 CN disclosed
US-20200048161-A1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608302-A1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND Shin-Etsu Chemical Co., Ltd. (JP) 2020-02-12 EP disclosed
EP-3053906-B1 METHOD FOR PRODUCING ASYMMETRIC CONJUGATED DIYNE COMPOUND AND METHOD FOR PRODUCING Z,Z-CONJUGATED DIENE COMPOUND USING THE SAME SHINETSU CHEMICAL CO (JP) 2017-12-27 EP disclosed
US-9845304-B2 Method for producing asymmetric conjugated diyne compound and method for producing Z,Z-conjugated diene compound using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-19 US disclosed
US-20160229829-A1 Method for Producing Asymmetric Conjugated Diyne Compound and Method for Producing Z,Z-Conjugated Diene Compound Using the Same SHIN-ETSU CHEMICAL CO., LTD (JP) 2016-08-11 US disclosed
EP-3053906-A1 METHOD FOR PRODUCING ASYMMETRIC CONJUGATED DIYNE COMPOUND AND METHOD FOR PRODUCING Z,Z-CONJUGATED DIENE COMPOUND USING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2016-08-10 EP disclosed
WO-2011009934-A1 TRIS(1,2,3-TRIAZOL-4-YL)METHANE ORGANOMETALLIC COMPOUNDS AS CATALYSTS AND PROCESSES USING THEM. INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) 2011-01-27 WO disclosed
US-20090069569-A1 CYCLOADDITION OF AZIDES AND ALKYNES INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) 2009-03-12 US disclosed
US-3996270-A Intermediate for Gossyplure, the sex pheromone of the pink bollworm STORY CHEMICAL CORPORATION (US) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10781146-B2 Process for preparing a 5-alken-1-yne compound, (6Z)-1,1-dialkoxy-6-nonen-2-yne compound, (2E,6Z)-2,6-nonadienal and (2E)-cis-6,7-epoxy-2-nonenal, and 1,1-dialkoxy-6-nonen-2-yne compound CBR1, CBR3, DECR1 FAAH 2862/4885TRPV1 3206/4885F7 1967/4885
US-20200048161-A1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND CBR1, CBR3, DECR1 FAAH 2908/4885TRPV1 3271/4885F7 1815/4885
US-20090069569-A1 CYCLOADDITION OF AZIDES AND ALKYNES PF4, AFF4, FLI1 FAAH 2257/4885TRPV1 3383/4885F7 570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.