Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365677 | 1.00 | LMNA (0.46) | LMNAMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9366555 | 0.88 | ALDH1A1 (0.48) | LMNAMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL9366552 | 0.88 | ALDH1A1 (0.48) | LMNAMEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL9366481 | 0.88 | LMNA (0.52) | LMNAMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9366482 | 0.88 | LMNA (0.52) | LMNAMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9366567 | 0.88 | LMNA (0.52) | LMNAMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9365679 | 0.87 | LMNA (0.53) | LMNAMEN1ALDH1A1KMT2ACYP1B1 | |
| SCHEMBL9365675 | 0.87 | LMNA (0.53) | LMNAMEN1ALDH1A1KMT2ACYP1B1 | |
| SCHEMBL9365482 | 0.86 | KMT2A (0.48) | LMNAMEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9365498 | 0.86 | LMNA (0.48) | LMNAMEN1ALDH1A1KMT2ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |