Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 4/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192276 | 0.89 | LMNA (0.56) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4418569 | 0.88 | MEN1 (0.51) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9365721 | 0.81 | LMNA (0.49) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9365789 | 0.81 | KMT2A (0.72) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29624123 | 0.81 | KMT2A (0.72) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9366734 | 0.80 | LMNA (0.54) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6195842 | 0.80 | LMNA (0.56) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9369551 | 0.77 | SMN1; SMN2 (0.58) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9366700 | 0.77 | MEN1 (0.52) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4429170 | 0.76 | LMNA (0.67) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |