Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366148 | 1.00 | PNP (0.49) | PNPCYP3A4MAPTADORA3TLR7 | |
| SCHEMBL9366146 | 0.88 | PNP (0.60) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9366153 | 0.88 | PNP (0.60) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9366083 | 0.86 | PNP (0.49) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9366087 | 0.86 | PNP (0.49) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9367067 | 0.77 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL9020125 | 0.77 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL10516308 | 0.77 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL10516867 | 0.77 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL19033338 | 0.76 | PNP (0.54) | PNPCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322854-B1 | Purinyl cyclobutanes | SQUIBB & SONS INC (US) | 1994-07-13 | — | — | EP | claimed |
| US-4918075-A | Purinyl and pyrimidinyl cyclobutanes and their use as antiviral agents | E. R. SQUIBB & SONS, INC. (US) | 1990-04-17 | — | — | US | claimed |
| EP-0322854-A1 | Purinyl cyclobutanes | E.R. Squibb & Sons, Inc. (US) | 1989-07-05 | — | — | EP | claimed |
| EP-0322854-B1 | Purinyl cyclobutanes | SQUIBB & SONS INC (US) | 1994-07-13 | — | — | EP | disclosed |
| US-4918075-A | Purinyl and pyrimidinyl cyclobutanes and their use as antiviral agents | E. R. SQUIBB & SONS, INC. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0322854-A1 | Purinyl cyclobutanes | E.R. Squibb & Sons, Inc. (US) | 1989-07-05 | — | — | EP | disclosed |