Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 11/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366153 | 1.00 | PNP (0.60) | PNPCYP3A4MAPTADORA3MEN1 | |
| SCHEMBL9366083 | 0.88 | PNP (0.49) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9366143 | 0.88 | PNP (0.49) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9366087 | 0.88 | PNP (0.49) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9366148 | 0.88 | PNP (0.49) | PNPCYP3A4MAPTADORA3 | |
| SCHEMBL9367067 | 0.79 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL9020125 | 0.79 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL10516308 | 0.79 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL10516867 | 0.79 | AHCY (0.60) | PNPADORA3 | |
| SCHEMBL6977161 | 0.76 | TLR7 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322854-B1 | Purinyl cyclobutanes | SQUIBB & SONS INC (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0322854-B1 | Purinyl cyclobutanes | SQUIBB & SONS INC (US) | 1994-07-13 | — | — | EP | disclosed |