Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 9/20 | 0.53 |
| ▸ | DRD3 | P35462 | 9/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366139 | 1.00 | OPRK1 (0.62) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL9133693 | 1.00 | OPRK1 (0.62) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| Bromide SCHEMBL9688047 | 0.98 | OPRK1 (0.60) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL9361129 | 0.93 | DRD3 (0.62) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL9362347 | 0.93 | DRD3 (0.62) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL3144639 | 0.93 | DRD3 (0.62) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL5661590 | 0.84 | CYP19A1 (0.61) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL31541205 | 0.83 | CYP19A1 (0.60) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL630379 | 0.83 | CYP19A1 (0.60) | OPRK1CYP19A1DRD2DRD3CYP26A1 | |
| SCHEMBL6156864 | 0.80 | CYP19A1 (0.57) | OPRK1CYP19A1DRD2DRD3CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436435-B1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | SANOFI ELF (FR) | 1994-03-23 | — | — | EP | disclosed |
| EP-0436435-A1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1991-07-10 | — | — | EP | disclosed |