Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361401 | 0.88 | LOXL2 (0.46) | LOXL2CYP4F2CYP4A11POLBMAPK10 | |
| SCHEMBL9366322 | 0.88 | RAB9A (0.41) | LOXL2POLBKDM4EALDH1A1RAB9A | |
| SCHEMBL9361328 | 0.84 | HPGD (0.43) | LOXL2CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL9361028 | 0.84 | POLB (0.41) | POLBSLC7A5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9361737 | 0.78 | LOXL2 (0.50) | LOXL2CYP4F2CYP4A11POLBMAPK10 | |
| SCHEMBL9366126 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9361293 | 0.76 | CYP1A2 (0.47) | POLBKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9360896 | 0.75 | RAB9A (0.42) | LOXL2POLBKDM4ERAB9AMAPT | |
| SCHEMBL9360901 | 0.74 | CNR2 (0.43) | ALDH1A1RAB9AHPGDMAPTNPC1 | |
| SCHEMBL9362540 | 0.74 | CYP1A2 (0.42) | KDM4EALDH1A1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |