Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361328 | 0.89 | HPGD (0.43) | KDM4EHPGDALDH1A1NPSR1TSHR | |
| SCHEMBL9366300 | 0.86 | LCK (0.45) | KDM4EHPGDALDH1A1TSHRNCEH1 | |
| SCHEMBL9366322 | 0.85 | RAB9A (0.41) | KDM4EHPGDALDH1A1NPSR1TSHR | |
| SCHEMBL9361481 | 0.85 | ALDH1A1 (0.49) | KDM4EHPGDALDH1A1NPSR1TSHR | |
| SCHEMBL9361236 | 0.84 | SMN1; SMN2 (0.39) | KDM4EHPGDALDH1A1TSHRRAB9A | |
| SCHEMBL9366149 | 0.78 | LOXL2 (0.45) | KDM4EHPGDALDH1A1NPSR1RAB9A | |
| SCHEMBL9361028 | 0.77 | POLB (0.41) | KDM4EHPGDALDH1A1TSHRMAPT | |
| SCHEMBL9361030 | 0.76 | L3MBTL1 (0.43) | KDM4EHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL9361427 | 0.75 | LCK (0.45) | TSHRNCEH1RAB9AMAPTKMT2A | |
| SCHEMBL9361293 | 0.74 | CYP1A2 (0.47) | KDM4EHPGDALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |