Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356174 | 0.72 | HRH3 (0.37) | HRH3 | |
| SCHEMBL4233540 | 0.71 | AR (0.41) | — | |
| SCHEMBL4232397 | 0.71 | MYC (0.38) | HRH3ALDH1A1CHRNA3 | |
| SCHEMBL9366679 | 0.66 | ALDH1A1 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6HRH3 | |
| Hydrochloric Acid SCHEMBL4152474 | 0.65 | DRD3 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6HRH3 | |
| SCHEMBL4538423 | 0.64 | — | — | |
| SCHEMBL21219851 | 0.62 | HTR3E (0.54) | SLC6A4CYP2D6ALDH1A1HSD17B10CHRNA3 | |
| SCHEMBL10866515 | 0.62 | CYP2A6 (0.68) | CYP2D6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL2781194 | 0.59 | ALDH1A1 (0.56) | ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL19583380 | 0.58 | KMT2A (0.50) | ALDH1A1HIF1ACYP1B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306148-B1 | Azabicyclic ethers | WYETH JOHN & BROTHER LTD (GB) | 1994-01-12 | — | — | EP | claimed |