Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513567 | 0.88 | TDP1 (0.45) | GRM2TDP1LTA4H | |
| SCHEMBL1513569 | 0.88 | TDP1 (0.45) | GRM2TDP1LTA4H | |
| SCHEMBL8968056 | 0.87 | TDP1 (0.54) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL6902066 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7838171 | 0.83 | GRM2 (0.55) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7840000 | 0.83 | GRM2 (0.55) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7842308 | 0.83 | TAAR1 (0.57) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL1513703 | 0.83 | GRM2 (0.42) | ALDH1A1TP53SMN1; SMN2GRM2BACE1 | |
| SCHEMBL1513706 | 0.83 | GRM2 (0.42) | ALDH1A1TP53SMN1; SMN2GRM2BACE1 | |
| SCHEMBL1513709 | 0.83 | GRM2 (0.40) | ALDH1A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392929-B1 | 2-Amino-5-aryloxymethyl-5-oxazoline derivatives and salts | SARGET LAB (FR) | 1994-01-12 | — | — | EP | claimed |