Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840000 | 0.84 | GRM2 (0.55) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7842308 | 0.84 | TAAR1 (0.57) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7838171 | 0.84 | GRM2 (0.55) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL8968056 | 0.83 | TDP1 (0.54) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL9366247 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3147892 | 0.81 | GRM2 (0.57) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3143188 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7840024 | 0.81 | GRM2 (0.57) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7840051 | 0.79 | CHRNB2 (0.49) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3144469 | 0.78 | RAB9A (0.42) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |