Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513567 | 0.91 | TDP1 (0.45) | TDP1GRM2NPC1RAB9A | |
| SCHEMBL1513569 | 0.91 | TDP1 (0.45) | TDP1GRM2NPC1RAB9A | |
| SCHEMBL4429915 | 0.89 | GRM2 (0.44) | TDP1GRM2NPC1RAB9A | |
| SCHEMBL9366247 | 0.87 | ALDH1A1 (0.44) | TDP1GRM2TAAR1ALDH1A1TP53 | |
| SCHEMBL3139586 | 0.85 | MEN1 (0.64) | TDP1GRM2ALDH1A1TP53TSHR | |
| SCHEMBL3144448 | 0.85 | GRM2 (0.49) | TDP1GRM2NPC1RAB9A | |
| SCHEMBL1513808 | 0.84 | TSHR (0.41) | TDP1GRM2ALDH1A1TP53CYP3A4 | |
| SCHEMBL3135510 | 0.84 | GRM2 (0.50) | GRM2NPC1RAB9A | |
| SCHEMBL1513582 | 0.84 | TSHR (0.41) | TDP1GRM2ALDH1A1TP53CYP3A4 | |
| SCHEMBL3144268 | 0.84 | ALOX5 (0.39) | TDP1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554728-B1 | Mixtures that are storage-stable at room temperature and their use as binders in coating compositions | BAYER AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| US-5292807-A | Compositions of cyclic isourea component with carboxyl component | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| EP-0554728-A2 | Mixtures that are storage-stable at room temperature and their use as binders in coating compositions | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |