Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367525 | 0.90 | NR3C1 (0.43) | SMN1; SMN2NPY5RNR3C1NPC1RAB9A | |
| SCHEMBL9366543 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2GAACNR2HDAC1HDAC6 | |
| SCHEMBL9483402 | 0.89 | PTGES (0.47) | SMN1; SMN2GAATSHRMAPTNPSR1 | |
| SCHEMBL9483626 | 0.89 | MEN1 (0.53) | SMN1; SMN2NPY5RNR3C1NPC1RAB9A | |
| SCHEMBL9367552 | 0.89 | GRM2 (0.44) | SMN1; SMN2NPY5RNR3C1NPC1RAB9A | |
| SCHEMBL9483910 | 0.86 | TDP1 (0.53) | SMN1; SMN2GAACNR2HDAC1HDAC6 | |
| SCHEMBL656591 | 0.86 | CNR2 (0.52) | SMN1; SMN2GAACNR2HDAC1HDAC6 | |
| SCHEMBL9369800 | 0.84 | GAA (0.48) | SMN1; SMN2NPC1RAB9AGAACNR2 | |
| SCHEMBL9484839 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2GAATSHRALDH1A1MAPT | |
| SCHEMBL11244931 | 0.82 | NPC1 (0.56) | SMN1; SMN2NPY5RNR3C1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409163-B1 | Novel cyclic vinylogous N-hydroxy-N-methylureas useful as 5-lipoxygenase inhibitors | MERRELL DOW PHARMA (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5191089-A | Herbicides for weeds that don't harm soybeans, corn, cotton or barley | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |