SCHEMBL9483402

SCHEMBL9483402

CCOC(=O)CN(C(=O)Cc1cccc(Oc2ccccc2)c1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGES O14684 2/20 0.47
ALOX5 P09917 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
CCR8 P51685 1/20 0.46
FDFT1 P37268 2/20 0.45
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
P2RX3 P56373 2/20 0.42
LTB4R Q15722 1/20 0.42
LTB4R2 Q9NPC1 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
FFAR1 O14842 1/20 0.42
CETP P11597 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9366335 0.89 SMN1; SMN2 (0.49) SMN1; SMN2GAAMAPTNPSR1TSHR
SCHEMBL9484182 0.89 MAPK14 (0.44) KDM4EMEN1KMT2AMAPTTDP1
SCHEMBL9366543 0.86 SMN1; SMN2 (0.56) SMN1; SMN2KDM4EGAATDP1NPSR1
SCHEMBL9486992 0.85 MAPK14 (0.49) KDM4EMEN1KMT2AMAPT
SCHEMBL6115348 0.83 CCR8 (0.54) PTGESSMN1; SMN2CCR8FDFT1MEN1
SCHEMBL9369800 0.83 GAA (0.48) PTGESALOX5SMN1; SMN2KDM4EGAA
SCHEMBL9484793 0.81 HTT (0.49) SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL9367525 0.80 NR3C1 (0.43) SMN1; SMN2KDM4EGAAMAPTTDP1
SCHEMBL9483919 0.80 SMN1; SMN2 (0.44) ALOX5SMN1; SMN2GAAMEN1KMT2A
SCHEMBL9484839 0.80 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5191089-A Herbicides for weeds that don't harm soybeans, corn, cotton or barley BAYER AKTIENGESELLSCHAFT (DE) 1993-03-02 US disclosed