SCHEMBL9366374

SCHEMBL9366374

Nc1ncnc2c1ncn2[C@@H]1C[C@H](CO)[C@H]1O

nearest known ligand 0.93

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 16/20 0.93
ADORA2B P29275 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10171758 1.00 AHCY (0.93) AHCYADORA2B
SCHEMBL9470693 1.00 AHCY (0.93) AHCYADORA2B
Aristeromycin SCHEMBL10353291 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL14515457 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL10353292 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL7534801 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12157242 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL9820408 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL692209 0.96 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12173988 0.96 AHCY (1.00) AHCYADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322854-B1 Purinyl cyclobutanes SQUIBB & SONS INC (US) 1994-07-13 EP claimed
US-4918075-A Purinyl and pyrimidinyl cyclobutanes and their use as antiviral agents E. R. SQUIBB & SONS, INC. (US) 1990-04-17 US claimed
EP-0322854-A1 Purinyl cyclobutanes E.R. Squibb & Sons, Inc. (US) 1989-07-05 EP claimed
EP-0322854-B1 Purinyl cyclobutanes SQUIBB & SONS INC (US) 1994-07-13 EP disclosed
US-4918075-A Purinyl and pyrimidinyl cyclobutanes and their use as antiviral agents E. R. SQUIBB & SONS, INC. (US) 1990-04-17 US disclosed
EP-0330992-A2 Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them Nippon Kayaku Kabushiki Kaisha (JP) 1989-09-06 EP disclosed
US-4855466-A Purinyl cyclobutanes E. R. SQUIBB & SONS, INC. (US) 1989-08-08 US disclosed
EP-0322854-A1 Purinyl cyclobutanes E.R. Squibb & Sons, Inc. (US) 1989-07-05 EP disclosed