Aristeromycin

Aristeromycin

SCHEMBL692209

Nc1ncnc2c1ncn2[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 16/20 1.00
ADORA2B P29275 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aristeromycin SCHEMBL10353292 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12280589 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL10353291 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL14515457 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL29695815 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12173988 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL7534801 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL9820408 1.00 AHCY (1.00) AHCYADORA2B
Aristeromycin SCHEMBL12157242 1.00 AHCY (1.00) AHCYADORA2B
SCHEMBL15297972 0.99 AHCY (0.97) AHCYADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4714452-A1 METHODS FOR TREATING SARS COV-2 INFECTIONS Gilead Sciences, Inc. (US) 2026-03-25 EP claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
US-11660307-B2 Methods for treating SARS CoV-2 infections GILEAD SCIENCES, INC. (US) 2023-05-30 US claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP claimed
WO-2022160323-A1 APPLICATION OF NUCLEOSIDE ANALOGUE IN PREPARATION OF DRUGS FOR PREVENTING OR TREATING GASTROINTESTINAL DISEASES 兰州大学 2022-08-04 WO claimed
CN-114533739-A Application of nucleoside analogue in preparing medicine for preventing or treating gastrointestinal tract diseases 兰州大学 2022-05-27 CN claimed
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES Spectral Analytics, Inc. (US) 2021-09-30 US claimed
WO-2021074443-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2021-04-22 WO claimed
US-20160250247-A1 VITAMIN B6 DERIVATIVES OF NUCLEOTIDES, ACYCLONUCLEOTIDES AND ACYCLONUCLEOSIDE PHOSPHONATES MBC PHARMA, INC. 2016-09-01 US claimed
WO-1996020010-A1 COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC ORIDIGM CORPORATION (US) 1996-07-04 WO claimed
EP-0334361-B1 Novel acetylenic, cyano and allenic aristeromycin/adenosine derivatives MERRELL DOW PHARMA (US) 1995-04-19 EP claimed
CN-1023804-C Novel acetylenic, cyano and allenic aristeromycin/adenosine derivatives MERRELL DOW PHARMA (US) 1994-02-16 CN claimed
CN-1023561-C Process for preparing cryptoclindamycin/adenosine derivatives MERRELL DOW PHARMA (US) 1994-01-19 CN claimed
CN-1036579-A Novel acetylenic, cyano group and allenic aristeromycin element/adenosine derivative MERRELL DOW PHARMA (US) 1989-10-25 CN claimed
EP-0334361-A2 Novel acetylenic, cyano and allenic aristeromycin/adenosine derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1989-09-27 EP claimed
CN-1033632-A NOVEL ARISTEROMYCIN/ADENOSINE DERIVATIVES MERRELL DOW PHARMA (US) 1989-07-05 CN claimed
EP-0304889-A2 Novel aristeromycin/adenosine derivatives MERRELL PHARMACEUTICALS INC. (US) 1989-03-01 EP claimed
US-4740598-A Conversion of aristeromycin into cyclaradine SCHERING CORPORATION (US) 1988-04-26 US claimed
EP-0246605-A2 Conversion of aristeromycin into cyclaradine SCHERING CORPORATION (US) 1987-11-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 AHCY 3684/4885ADORA2B 2265/4885
US-20160250247-A1 VITAMIN B6 DERIVATIVES OF NUCLEOTIDES, ACYCLONUCLEOTIDES AND ACYCLONUCLEOSIDE PHOSPHONATES PNPO, PNP, PPA1 AHCY 249/4885ADORA2B 17/4885
US-11660307-B2 Methods for treating SARS CoV-2 infections ACE2, ACE, PNP AHCY 921/4885ADORA2B 836/4885
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES NCOA1, NCOA2, NCOA3 AHCY 3060/4885ADORA2B 3923/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF AHCY 4462/4885ADORA2B 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.