Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.63 |
| ▸ | HMGCR | P04035 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26624468 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL3626347 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL28743000 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL26251491 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL5375334 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL2123036 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL10404839 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL11045543 | 0.98 | PTPN7 (0.67) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL11328048 | 0.96 | PTPN7 (0.64) | PTPN7HMGCRTDP1ALDH1A1MAPT | |
| SCHEMBL26624663 | 0.94 | PTPN7 (0.68) | PTPN7HMGCRTDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450742-B1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-07-06 | — | — | EP | claimed |
| EP-0214616-A2 | Acetylenic prostaglandins | G.D. Searle & Co. (US) | 1987-03-18 | — | — | EP | claimed |
| US-20140199243-A1 | BIFUNCTIONAL PHOSPHONATE CHELATING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-17 | — | — | US | disclosed |
| US-20140199243-A1 | BIFUNCTIONAL PHOSPHONATE CHELATING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-17 | — | — | US | disclosed |
| WO-2014070092-A1 | FUNCTIONALIZED CELLULOSE NANOCRYSTALS, A METHOD FOR THE PREPARATION THEREOF AND USE OF FUNCTIONALIZED CELLULOSE NANOCRYSTALS IN COMPOSITES AND FOR GRAFTING | SWETREE TECHNOLOGIES AB (SE) | 2014-05-08 | — | — | WO | disclosed |
| WO-2012172271-A1 | BIFUNCTIONAL PHOSPHONATE CHELATING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-12-20 | — | — | WO | disclosed |
| US-7446226-B2 | Phenylhept-6-yne-acid-4-hydroxy-3-methoxylbenzylamide (phenylcapsaicin); use as microorganism repellent agents in paints and coatings, for marine installations and ships, but also for land-based structures; nontoxic | AXIMED AS (NO) | 2008-11-04 | — | — | US | disclosed |
| US-20070167524-A1 | Capsaicin derivates and the production and use thereof | AXICHEM AB (SE) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167524-A1 | Capsaicin derivates and the production and use thereof | TRPV1, TRPA1, TRPV2 | PTPN7 1874/4885HMGCR 1657/4885TDP1 2585/4885 |
| US-20140199243-A1 | BIFUNCTIONAL PHOSPHONATE CHELATING AGENTS | PHOSPHO1, ATIC, HLA-C | PTPN7 863/4885HMGCR 4139/4885TDP1 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.