Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 9/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365734 | 0.88 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9366719 | 0.86 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9366734 | 0.84 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9365721 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9366700 | 0.78 | MEN1 (0.52) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9369551 | 0.78 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4429170 | 0.77 | LMNA (0.67) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29624123 | 0.75 | KMT2A (0.72) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9365789 | 0.75 | KMT2A (0.72) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9365834 | 0.74 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |