Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342494 | 0.85 | LMNA (0.75) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9369302 | 0.84 | LMNA (0.78) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365388 | 0.83 | LMNA (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365789 | 0.83 | KMT2A (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8342323 | 0.83 | LMNA (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29624123 | 0.83 | KMT2A (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4431508 | 0.82 | LMNA (0.54) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365701 | 0.80 | LMNA (0.79) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8342786 | 0.80 | LMNA (0.68) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8343305 | 0.80 | LMNA (0.68) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |