Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724548 | 0.89 | TSHR (0.55) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9367530 | 0.81 | TSHR (0.51) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9371007 | 0.81 | KMT2A (0.49) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9373872 | 0.79 | CYP2C9 (0.46) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9369978 | 0.78 | MDM4 (0.52) | TSHRKMT2AKDM4EMEN1LMNA | |
| SCHEMBL9375173 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL9373932 | 0.77 | MDM4 (0.51) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9376289 | 0.77 | CYP2C9 (0.42) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9370377 | 0.77 | CYP2C9 (0.44) | TSHRCYP2C9KMT2ARECQLKDM4E | |
| SCHEMBL9370626 | 0.77 | KMT2A (0.53) | TSHRCYP2C9KMT2ARECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304057-B1 | Pyridinone derivatives, and agricultural and horticultural fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-04-20 | — | — | EP | disclosed |
| EP-0304057-A2 | Pyridinone derivatives, and agricultural and horticultural fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |