Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 12/20 | 0.40 |
| ▸ | MDM4 | O15151 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.37 |
| ▸ | GLS2 | Q9UI32 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370230 | 0.87 | TSHR (0.40) | CYP2C9HTTTSHRMDM2MDM4 | |
| SCHEMBL10724548 | 0.84 | TSHR (0.55) | CYP2C9HTTTSHRMDM2MDM4 | |
| SCHEMBL9373872 | 0.81 | CYP2C9 (0.46) | CYP2C9HTTTSHRMDM2KMT2A | |
| SCHEMBL9375173 | 0.80 | PTGS2 (0.53) | — | |
| SCHEMBL9370377 | 0.78 | CYP2C9 (0.44) | CYP2C9HTTTSHRMDM2MDM4 | |
| SCHEMBL9367118 | 0.77 | TSHR (0.46) | CYP2C9HTTTSHRMDM2KMT2A | |
| SCHEMBL9371007 | 0.77 | KMT2A (0.49) | CYP2C9HTTTSHRKMT2AKDM4E | |
| SCHEMBL9367530 | 0.77 | TSHR (0.51) | CYP2C9HTTTSHRKMT2AKDM4E | |
| SCHEMBL9369978 | 0.75 | MDM4 (0.52) | HTTTSHRMDM2MDM4KMT2A | |
| SCHEMBL9370303 | 0.74 | ALDH1A1 (0.46) | CYP2C9HTTTSHRMDM2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239391-B1 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-4871751-A | 1,2,6-Triphenyl-4(1H)-pyridinone derivatives, and their use as fungicides | KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4757081-A | Agriculture, horticulture | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0239391-A2 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |