Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369827 | 0.87 | LMNA (0.45) | PTGS2PTGS1ALOX5 | |
| SCHEMBL10724548 | 0.85 | TSHR (0.55) | — | |
| SCHEMBL9373872 | 0.82 | CYP2C9 (0.46) | PTGS2PTGS1 | |
| SCHEMBL9376289 | 0.80 | CYP2C9 (0.42) | — | |
| SCHEMBL9370377 | 0.80 | CYP2C9 (0.44) | PTGS2 | |
| SCHEMBL9367118 | 0.78 | TSHR (0.46) | PTGS2PTGS1 | |
| SCHEMBL9371007 | 0.78 | KMT2A (0.49) | — | |
| SCHEMBL9367530 | 0.78 | TSHR (0.51) | — | |
| SCHEMBL4842319 | 0.77 | PTGS2 (0.51) | PTGS2PTGS1ALOX5 | |
| SCHEMBL9369978 | 0.76 | MDM4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239391-B1 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-4871751-A | 1,2,6-Triphenyl-4(1H)-pyridinone derivatives, and their use as fungicides | KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4757081-A | Agriculture, horticulture | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0239391-A2 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |