Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142948 | 0.87 | GAA (0.52) | GAATSHRPOLBGLAKDM4E | |
| SCHEMBL9187870 | 0.81 | TSHR (0.44) | GAATSHRPOLBGLAKDM4E | |
| SCHEMBL9367201 | 0.79 | ALDH1A1 (0.42) | GAATSHRPOLBGLAKDM4E | |
| SCHEMBL9814418 | 0.79 | KIF11 (0.40) | POLBKDM4EMEN1KMT2AMAPT | |
| SCHEMBL10498338 | 0.78 | MAPT (0.46) | GAATSHRPOLBGLAKDM4E | |
| SCHEMBL9367884 | 0.77 | KDM4E (0.45) | GAATSHRPOLBKDM4EMEN1 | |
| SCHEMBL9447622 | 0.76 | KDM4E (0.45) | GAATSHRPOLBGLAKDM4E | |
| Hydrochloric Acid SCHEMBL10497798 | 0.76 | MAPT (0.45) | GAATSHRPOLBGLAKDM4E | |
| SCHEMBL10766283 | 0.76 | TSHR (0.47) | GAATSHRPOLBGLAKDM4E | |
| SCHEMBL1013276 | 0.76 | GAA (0.50) | GAATSHRPOLBGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251013-B1 | FLUORINE CONTAINING O-AMINOPHENOLS | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |
| EP-0251013-A2 | Fluorine containing o-aminophenols | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |