Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496333 | 0.80 | EGLN1 (0.37) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| Hydrochloric Acid SCHEMBL29277291 | 0.78 | EGLN1 (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL2558809 | 0.78 | HMGCR (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL8076135 | 0.77 | — | — | |
| SCHEMBL23553761 | 0.76 | CTH (0.33) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL15542520 | 0.76 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL18509319 | 0.76 | CTH (0.38) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL31000606 | 0.74 | NAALAD2 (0.32) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7571808 | 0.74 | HMGCR (0.37) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL22694095 | 0.73 | POLB (0.32) | ALDH1A1TDP1CTHHMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2012-03-15 | — | — | US | claimed |
| EP-2425861-A1 | RADIOACTIVELY LABELED SUBSTANCE | National University Corporation Chiba University (JP) | 2012-03-07 | — | — | EP | claimed |
| US-20120065367-A1 | Radioactively Labeled Substance | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2425861-A1 | RADIOACTIVELY LABELED SUBSTANCE | National University Corporation Chiba University (JP) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | KIT, ABCG2, TK1 | ALDH1A1 2232/4885LMNA 3375/4885MAPT 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.