Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MYOC | Q99972 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367406 | 0.89 | KMT2A (0.77) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL16922176 | 0.88 | KMT2A (0.81) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL642700 | 0.88 | KMT2A (0.81) | MAPTKMT2AMEN1ALDH1A1POLB | |
| Phosphine SCHEMBL28320532 | 0.87 | KMT2A (0.78) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3037119 | 0.87 | HTR2A (0.68) | MAPTKMT2AMEN1ALDH1A1POLB | |
| Acetic Acid SCHEMBL28965272 | 0.85 | GAA (0.62) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL26374 | 0.85 | GAA (0.65) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL14808444 | 0.85 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13350950 | 0.84 | GAA (0.54) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL16270980 | 0.84 | MAPT (0.55) | MAPTKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024055-B2 | Acetaminophen conjugates, compositions and methods of use thereof | ACORDA THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-9024055-B2 | Acetaminophen conjugates, compositions and methods of use thereof | ACORDA THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140243407-A1 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF | ACCORDA THERAPEUTICS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243407-A1 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF | ACCORDA THERAPEUTICS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| EP-2758133-A1 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF | Acorda Therapeutics, Inc. (US) | 2014-07-30 | — | — | EP | disclosed |
| US-8575217-B2 | Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-11-05 | — | — | US | disclosed |
| US-8575217-B2 | Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-11-05 | — | — | US | disclosed |
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-24 | — | — | US | disclosed |
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-24 | — | — | US | disclosed |
| US-20130267726-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-10 | — | — | US | disclosed |
| US-20130267726-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-10 | — | — | US | disclosed |
| US-8466197-B2 | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-06-18 | — | — | US | disclosed |
| US-8466197-B2 | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-06-18 | — | — | US | disclosed |
| WO-2013044064-A1 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF | NEUROGESX, INC. (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013044064-A1 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF | NEUROGESX, INC. (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2012080371-A1 | NEW THIOCARBONATES AS ANTI-INFLAMMATORY AND ANTIOXIDANT COMPOUNDS USEFUL FOR TREATING METABOLIC DISORDERS | GENMEDICA THERAPEUTICS SL (ES) | 2012-06-21 | — | — | WO | disclosed |
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2012-06-14 | — | — | US | disclosed |
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2012-06-14 | — | — | US | disclosed |
| US-20100234452-A1 | Anti-Inflammatory and Antioxidant Conjugates Useful for Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2010-09-16 | — | — | US | disclosed |
| US-20100234452-A1 | Anti-Inflammatory and Antioxidant Conjugates Useful for Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | HSD17B14, SORD, GPX4 | MAPT 3367/4885KMT2A 3962/4885MEN1 2842/4885 |
| US-20140243407-A1 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF | UGT1A1, UGT1A3, GSTA1 | MAPT 1039/4885KMT2A 2908/4885MEN1 4562/4885 |
| US-20100234452-A1 | Anti-Inflammatory and Antioxidant Conjugates Useful for Treating Metabolic Disorders | HSD17B14, SORD, GPX4 | MAPT 3367/4885KMT2A 3962/4885MEN1 2842/4885 |
| US-20130267726-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | CPT1B, LTC4S, TXNRD2 | MAPT 1844/4885KMT2A 4274/4885MEN1 4753/4885 |
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | CPT1B, LTC4S, TXNRD2 | MAPT 1844/4885KMT2A 4274/4885MEN1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.