Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | PYGB | P11216 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936768 | 1.00 | CYP3A4 (0.48) | CYP3A4MAPK1MMP1MMP2MMP3 | |
| SCHEMBL958295 | 0.92 | IL1RN (0.37) | CYP3A4MAPK1MMP1MMP2MMP3 | |
| SCHEMBL958294 | 0.92 | IL1RN (0.37) | CYP3A4MAPK1MMP1MMP2MMP3 | |
| SCHEMBL1055434 | 0.85 | ECE1 (0.45) | MMP1MMP2MMP9ECE1ERAP2 | |
| SCHEMBL935825 | 0.85 | ECE1 (0.45) | MMP1MMP2MMP9ECE1ERAP2 | |
| SCHEMBL1045846 | 0.85 | ECE1 (0.45) | MMP1MMP2MMP9ECE1ERAP2 | |
| SCHEMBL935823 | 0.85 | ECE1 (0.45) | MMP1MMP2MMP9ECE1ERAP2 | |
| SCHEMBL935541 | 0.84 | METAP2 (0.42) | ALDH1A1 | |
| SCHEMBL937269 | 0.84 | POLB (0.36) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL937268 | 0.84 | POLB (0.36) | MMP1MMP2MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |