Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370055 | 0.89 | DRD2 (0.49) | DRD2DRD4HTR2AHTR2C | |
| SCHEMBL7783724 | 0.89 | DRD2 (0.54) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL9371451 | 0.88 | DRD2 (0.56) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL9367241 | 0.85 | DRD2 (0.45) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL7783722 | 0.82 | DRD2 (0.58) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL7792010 | 0.82 | DRD2 (0.58) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL13648727 | 0.80 | DRD2 (0.62) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL9367644 | 0.80 | DRD3 (0.55) | DRD2DRD4HTR2AHTR2CDRD3 | |
| SCHEMBL9367787 | 0.79 | — | — | |
| SCHEMBL9367275 | 0.78 | DRD2 (0.55) | DRD2DRD4HTR2AHTR2CDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431579-B1 | Substituted cyclohexenes as central nervous system agents | WARNER LAMBERT CO (US) | 1994-07-27 | — | — | EP | claimed |
| EP-0431579-A2 | Substituted cyclohexenes as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | claimed |
| EP-0431579-B1 | Substituted cyclohexenes as central nervous system agents | WARNER LAMBERT CO (US) | 1994-07-27 | — | — | EP | disclosed |
| EP-0431579-A2 | Substituted cyclohexenes as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4975445-A | Antidepressants | WARNER-LAMBERT COMPANY (US) | 1990-12-04 | — | — | US | disclosed |