Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566280 | 1.00 | CYP2A6 (0.54) | CYP2A6CYP1A2NQO1HSD17B1HSD17B2 | |
| SCHEMBL936825 | 0.96 | CYP2A6 (0.50) | CYP2A6CYP1A2NQO1HSD17B1HSD17B2 | |
| SCHEMBL29566275 | 0.86 | CYP2A6 (0.48) | CYP2A6CYP1A2NQO1HSD17B1HSD17B2 | |
| SCHEMBL29870412 | 0.82 | CYP1A1 (0.54) | CYP2A6CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL1478481 | 0.82 | CYP1A1 (0.54) | CYP2A6CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL187127 | 0.80 | CA1 (0.58) | KDM4ERAB9AMEN1MAPK1KMT2A | |
| SCHEMBL21715140 | 0.80 | SLC6A2 (0.37) | CYP2A6CYP1A2HPGDSKDM4EGSTP1 | |
| SCHEMBL10481157 | 0.79 | CYP1A1 (0.52) | CYP1A1CYP1B1 | |
| SCHEMBL9743076 | 0.79 | APP (0.59) | CYP2A6CYP1A2NQO1HSD17B1HSD17B2 | |
| SCHEMBL31499214 | 0.79 | NQO1 (0.62) | CYP2A6CYP1A2NQO1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731570-A2 | GAMMA-GRAPHYNE AND METHODS OF FABRICATION | CASE WESTERN RESERVE UNIVERSITY (US) | 2026-04-29 | — | — | EP | claimed |
| WO-2024264047-A2 | GAMMA-GRAPHYNE AND METHODS OF FABRICATION | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-12-26 | — | — | WO | claimed |
| US-11814462-B2 | Functionalized cyclic polymers and methods of preparing same | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-14 | — | — | US | claimed |
| CN-114874088-A | Acetylenic acid and preparation method thereof | 中国科学院上海高等研究院 | 2022-08-09 | — | — | CN | claimed |
| US-20220056167-A1 | Functionalized Cyclic Polymers and Methods of Preparing Same | NATIONAL SCIENCE FOUNDATION | 2022-02-24 | — | — | US | claimed |
| WO-2020223672-A1 | FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME | UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) | 2020-11-05 | — | — | WO | claimed |
| EP-3768672-B1 | 3-(HYDROXY)-PYRIDIN-4(1H)-ONE COMPOUNDS AND METHODS OF USING THE SAME | GEORGIA TECH RES INST (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12521382-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2026-01-13 | — | — | US | disclosed |
| US-20250268880-A1 | 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same | GEORGIA TECH RESEARCH CORPORATION | 2025-08-28 | — | — | US | disclosed |
| US-12324803-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250122133-A1 | Selective Transition Metal Catalyzed Deuterium Incorporation Into Alkyne and Alkene Functionalities | MARQUETTE UNIVERSITY | 2025-04-17 | — | — | US | disclosed |
| CN-112390814-B | Combination of an EP4 receptor antagonist and a PD-1 inhibitor for the treatment of cancer | 上海宇耀生物科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-114516789-B | Cyclopropenones micromolecule compound and synthetic method and application thereof | 暨南大学 | 2023-12-05 | — | — | CN | disclosed |
| EP-1401822-A1 | NAPHTHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | Wyeth (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6599925-B2 | Cardiovascular disorders; anticancer agents | WYETH | 2003-07-29 | — | — | US | disclosed |
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH | 2003-01-23 | — | — | US | disclosed |
| WO-2003000671-A1 | NAPHTHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2003-01-03 | — | — | WO | disclosed |
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4011339-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-3987116-A | ETHYNYLARYL COMPOUNDS AND DERIVATIVES THEREOF | WILLIAM H. RORER, INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122133-A1 | Selective Transition Metal Catalyzed Deuterium Incorporation Into Alkyne and Alkene Functionalities | HDHD5, DDT, AHR | CYP2A6 87/4885CYP1A2 81/4885NQO1 15/4885 |
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | F2R, SERPINE1, SERPINC1 | CYP2A6 1231/4885CYP1A2 1023/4885NQO1 2696/4885 |
| US-20250268880-A1 | 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same | KDM1B, KDM3A, KDM1A | CYP2A6 2718/4885CYP1A2 2929/4885NQO1 3437/4885 |
| US-12324803-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | KDM1B, KDM3A, KDM1A | CYP2A6 2718/4885CYP1A2 2929/4885NQO1 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.