SCHEMBL9368378

SCHEMBL9368378

CCCCCCCCCCCCCCCC(=O)OC(C)C(C)O

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.69
MAPT P10636 3/20 0.59
MAPK1 P28482 2/20 0.59
ALDH1A1 P00352 1/20 0.56
DGKA P23743 1/20 0.52
PRKCA P17252 1/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
DUSP3 P51452 1/20 0.50
GMNN O75496 1/20 0.47
HSP90AA1 P07900 1/20 0.47
BLM P54132 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NR1H4 Q96RI1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9730039 1.00 LMNA (0.69) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL9730568 1.00 LMNA (0.69) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL1700777 1.00 LMNA (0.69) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL9730256 1.00 LMNA (0.69) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL9731496 0.98 LMNA (0.66) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL9730301 0.92 LMNA (0.57) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL15300292 0.90 PRKCA (0.58) LMNAMAPTALDH1A1DGKAPRKCA
SCHEMBL10788026 0.90 PRKCA (0.58) LMNAMAPTALDH1A1DGKAPRKCA
SCHEMBL10788029 0.90 PRKCA (0.58) LMNAMAPTALDH1A1DGKAPRKCA
SCHEMBL11149299 0.90 LMNA (0.77) LMNAMAPTMAPK1ALDH1A1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0290420-B1 Shortening compositions containing polyol polyesters PROCTER & GAMBLE (US) 1994-01-12 EP disclosed
US-5021256-A Soft oil, hardstock fat and triglycerides THE PROCTER & GAMBLE COMPANY (US) 1991-06-04 US disclosed
US-4880657-A FATS, FOODS THE PROCTER & GAMBLE COMPANY (US) 1989-11-14 US disclosed
EP-0290420-A2 Shortening compositions containing polyol polyesters THE PROCTER & GAMBLE COMPANY (US) 1988-11-09 EP disclosed