Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731496 | 0.94 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730256 | 0.92 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL1700777 | 0.92 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9368378 | 0.92 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730568 | 0.92 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730039 | 0.92 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL27907269 | 0.89 | LMNA (0.52) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9730948 | 0.87 | ALDH1A1 (0.48) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL27694977 | 0.85 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11016719 | 0.84 | LMNA (0.40) | LMNAMAPTMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |