Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364712 | 0.89 | SMN1; SMN2 (0.67) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL9613726 | 0.86 | RAB9A (0.70) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL9613720 | 0.86 | RAB9A (0.70) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4812667 | 0.86 | MAPT (0.69) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL7162798 | 0.85 | RAB9A (0.64) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL978809 | 0.83 | RAB9A (0.73) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL978808 | 0.83 | RAB9A (0.73) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL8784838 | 0.83 | RAB9A (0.69) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL4810405 | 0.83 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL7556196 | 0.83 | SMN1; SMN2 (0.67) | MEN1KMT2ASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |