Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613726 | 1.00 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL978809 | 0.88 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL978808 | 0.88 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7162798 | 0.87 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9368595 | 0.86 | MEN1 (0.67) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL8784838 | 0.85 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5524662 | 0.84 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| Oxalic Acid SCHEMBL20984281 | 0.83 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL4812667 | 0.83 | MAPT (0.69) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7071559 | 0.82 | LMNA (0.76) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520024-A1 | QUINOXALINE COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-12-30 | — | — | EP | disclosed |
| WO-1991013878-A1 | QUINOXALINE COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-09-19 | — | — | WO | disclosed |