Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370974 | 0.81 | UNG (0.45) | AKR1C3AKR1C2PTGS1PTGS2ESR1 | |
| SCHEMBL9537546 | 0.81 | UNG (0.45) | AKR1C3AKR1C2PTGS1PTGS2ESR1 | |
| SCHEMBL6727057 | 0.79 | AKR1C3 (0.47) | AKR1C3AKR1C2PTGS1ALDH1A1NQO2 | |
| SCHEMBL9539944 | 0.74 | MAPT (0.44) | ALDH1A1POLBTDP1 | |
| SCHEMBL9368631 | 0.74 | MAPT (0.44) | ALDH1A1POLBTDP1 | |
| SCHEMBL9371236 | 0.72 | ALDH1A1 (0.50) | AKR1C3AKR1C2PTGS1ALDH1A1PTGS2 | |
| SCHEMBL9371234 | 0.72 | ALDH1A1 (0.50) | AKR1C3AKR1C2PTGS1ALDH1A1PTGS2 | |
| SCHEMBL13825371 | 0.72 | L3MBTL1 (0.38) | AKR1C3PTGS1ALDH1A1PTGS2ESR1 | |
| SCHEMBL9495763 | 0.71 | PTGS1 (0.44) | AKR1C3AKR1C2PTGS1ALDH1A1PTGS2 | |
| SCHEMBL9495769 | 0.71 | PTGS1 (0.44) | AKR1C3AKR1C2PTGS1ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |