Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592195 | 0.94 | DRD2 (0.54) | DRD2HTR1A | |
| SCHEMBL9373232 | 0.89 | DRD2 (0.56) | DRD2HTR1A | |
| SCHEMBL9368508 | 0.89 | HTR1A (0.59) | HTR1A | |
| SCHEMBL9373720 | 0.88 | DRD2 (0.46) | DRD2HTR1A | |
| SCHEMBL6588462 | 0.82 | DRD2 (0.54) | DRD2 | |
| SCHEMBL6591927 | 0.82 | — | — | |
| SCHEMBL9367716 | 0.79 | LMNA (0.58) | DRD2HTR1A | |
| SCHEMBL6589732 | 0.79 | DRD2 (0.54) | DRD2 | |
| Oxalic Acid SCHEMBL6778343 | 0.78 | DRD2 (0.49) | DRD2HTR1A | |
| SCHEMBL9180759 | 0.77 | HTR1A (0.63) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376607-B1 | Piperazinyl derivatives | LUNDBECK & CO AS H (DK) | 1994-03-02 | — | — | EP | disclosed |
| US-5002948-A | Central Nervous System Disorders | H. LUNDBECK A/S (DK) | 1991-03-26 | — | — | US | disclosed |
| EP-0376607-A1 | Piperazinyl derivatives | H. LUNDBECK A/S (DK) | 1990-07-04 | — | — | EP | disclosed |