Sugi Predict

Sugi Predict / Compounds / SCHEMBL9368669

SCHEMBL9368669

SCHEMBL9368669

CCCC(Nc1nc(NC(CCC)C2CC(C)(C)N(C)C(C)(C)C2)nc(N(C)CCCCCCN(C)c2nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)n2)n1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EHMT2 Q96KQ7 3/20 0.33
▸ EHMT1 Q9H9B1 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9373097 0.81 FLT3 (0.39) EHMT2EHMT1
SCHEMBL4280274 0.81 SMN1; SMN2 (0.34) —
SCHEMBL714017 0.80 GAA (0.36) —
SCHEMBL8838291 0.80 FLT3 (0.31) —
SCHEMBL698651 0.77 IDH1 (0.33) —
SCHEMBL3145310 0.76 KMT2A (0.36) —
SCHEMBL8549076 0.72 — —
SCHEMBL9742736 0.72 IDH1 (0.32) —
SCHEMBL7479465 0.72 — —
SCHEMBL11331850 0.71 CRHR1 (0.34) EHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0319480-B1 Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups CIBA GEIGY AG (CH) 1994-01-26 — — EP disclosed
US-5130429-A Methylation with formaldehyde in a solvent and distillation CIBA-GEIGY CORPORATION (US) 1992-07-14 — — US disclosed
EP-0319480-A2 Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups CIBA-GEIGY AG (CH) 1989-06-07 — — EP disclosed