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SCHEMBL4280274

SCHEMBL4280274

CCCC(Nc1nc(NCCCN(CCN(CCCNc2nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)n2)c2nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)n2)c2nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)nc(NC(CCC)C3CC(C)(C)N(C)C(C)(C)C3)n2)nc(NC(CCC)C2CC(C)(C)N(C)C(C)(C)C2)n1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ FLT3 P36888 1/20 0.33
▸ TYRO3 Q06418 1/20 0.33
▸ MERTK Q12866 1/20 0.33
▸ GAS6 Q14393 1/20 0.33
▸ SLC29A1 Q99808 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9373097 0.87 FLT3 (0.39) FLT3TYRO3MERTKGAS6
SCHEMBL294893 0.87 SLC29A1 (0.31) SMN1; SMN2SLC29A1
SCHEMBL9368669 0.81 EHMT2 (0.33) —
SCHEMBL9250895 0.77 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL11331850 0.77 CRHR1 (0.34) FLT3TYRO3MERTKGAS6
SCHEMBL4280278 0.77 SMN1; SMN2 (0.33) SMN1; SMN2FLT3TYRO3MERTKGAS6
SCHEMBL8838291 0.77 FLT3 (0.31) FLT3TYRO3MERTKGAS6
SCHEMBL714017 0.77 GAA (0.36) —
SCHEMBL9428711 0.76 SLC29A1 (0.33) SLC29A1
SCHEMBL10813594 0.76 KCNH3 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 — — EP claimed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 — — US claimed
US-20090075048-A1 Cellulose-mixed ester film and method for producing same FUJIFILM CORPORATION (JP) 2009-03-19 — — US disclosed
EP-0856526-B1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORP (JP) 2002-08-28 — — EP disclosed
US-6313225-B2 High melt tension, high crystallization temperature; hollow moldings CHISSO CORPORATION (JP) 2001-11-06 — — US disclosed
US-20010004657-A1 OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 2001-06-21 — — US disclosed
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 — — US disclosed
US-6156845-A Polyolefin composition and method of making CHISSO CORPORATION (JP) 2000-12-05 — — US disclosed
EP-0972800-A1 MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING CHISSO CORPORATION (JP) 2000-01-19 — — EP disclosed
EP-0856526-A1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 1998-08-05 — — EP disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 — — EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 — — US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 — — EP disclosed