Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541159 | 0.85 | SLC7A5 (0.50) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL9541373 | 0.84 | SLC7A5 (0.52) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL9372770 | 0.80 | SLC7A5 (0.46) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL15789270 | 0.80 | NR1H4 (0.51) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL9368860 | 0.79 | SLC7A5 (0.51) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL4332066 | 0.79 | HDAC1 (0.48) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7385091 | 0.78 | LOXL2 (0.55) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL1830055 | 0.77 | LOXL2 (0.54) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL1790854 | 0.76 | SLC7A5 (0.68) | SLC7A5LOXL2KDM4EALDH1A1MAPT | |
| SCHEMBL20236489 | 0.76 | HDAC1 (0.48) | LOXL2KDM4EALDH1A1HDAC1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |