Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541159 | 0.93 | SLC7A5 (0.50) | SLC7A5RAB9ANPC1LOXL2MAPT | |
| SCHEMBL9541373 | 0.90 | SLC7A5 (0.52) | SLC7A5RAB9ANPC1LOXL2MAPT | |
| SCHEMBL9376678 | 0.88 | PTGES (0.47) | RAB9ANPC1FOLH1PTGESALOX5 | |
| SCHEMBL9369194 | 0.88 | NPC1 (0.49) | SLC7A5RAB9ANPC1PTGESALOX5 | |
| SCHEMBL9372770 | 0.84 | SLC7A5 (0.46) | SLC7A5RAB9ANPC1LOXL2MAPT | |
| SCHEMBL9538478 | 0.81 | PTGES (0.53) | RAB9ANPC1PTGESALOX5KMT2A | |
| SCHEMBL1790854 | 0.81 | SLC7A5 (0.68) | SLC7A5RAB9ANPC1LOXL2MAPT | |
| SCHEMBL9372894 | 0.81 | PTGES (0.55) | RAB9ANPC1PTGESALOX5KMT2A | |
| SCHEMBL9368612 | 0.80 | PTGES (0.52) | RAB9ANPC1SMN1; SMN2PTGESALOX5 | |
| SCHEMBL9369673 | 0.79 | SLC7A5 (0.44) | SLC7A5RAB9ALOXL2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |