Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541373 | 0.97 | SLC7A5 (0.52) | SLC7A5PTGESALOX5RAB9AMAPT | |
| SCHEMBL9368860 | 0.93 | SLC7A5 (0.51) | SLC7A5PTGESALOX5RAB9AMAPT | |
| SCHEMBL9372770 | 0.91 | SLC7A5 (0.46) | SLC7A5PTGESALOX5RAB9AMAPT | |
| SCHEMBL9372894 | 0.87 | PTGES (0.55) | PTGESALOX5RAB9AHDAC11HDAC8 | |
| SCHEMBL9538478 | 0.87 | PTGES (0.53) | PTGESALOX5RAB9ANPC1LTC4S | |
| SCHEMBL9368612 | 0.86 | PTGES (0.52) | PTGESALOX5RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9369673 | 0.85 | SLC7A5 (0.44) | SLC7A5RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL9372874 | 0.85 | PTGES (0.55) | PTGESALOX5NPC1LTC4SNR1H4 | |
| SCHEMBL9369194 | 0.81 | NPC1 (0.49) | SLC7A5PTGESALOX5RAB9ANPC1 | |
| SCHEMBL9376678 | 0.81 | PTGES (0.47) | PTGESALOX5RAB9ANPC1LTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |