Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372262 | 0.99 | SIGMAR1 (0.56) | SIGMAR1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9371917 | 0.93 | HTR1A (0.55) | SIGMAR1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9375687 | 0.91 | HTR1A (0.55) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9371801 | 0.90 | HTR1A (0.54) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9370198 | 0.86 | HRH3 (0.50) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9374271 | 0.86 | HTR1A (0.46) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9369075 | 0.86 | HTR1A (0.46) | SIGMAR1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9371795 | 0.85 | DRD2 (0.64) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9371919 | 0.84 | DRD2 (0.58) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9372762 | 0.84 | DRD3 (0.61) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5071845-A | Psychotropic or anxyiolytic agent | SUNTORY LIMITED (JP) | 1991-12-10 | — | — | US | disclosed |