Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872327 | 0.84 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9369981 | 0.75 | BRD4 (0.33) | BRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6965129 | 0.71 | CHRM2 (0.47) | — | |
| SCHEMBL18998727 | 0.69 | — | — | |
| SCHEMBL19015348 | 0.69 | — | — | |
| SCHEMBL14086035 | 0.69 | — | — | |
| SCHEMBL8148238 | 0.69 | — | — | |
| SCHEMBL295218 | 0.69 | — | — | |
| SCHEMBL17147617 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL5200635 | 0.69 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307140-B1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0307140-A1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |