Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697278 | 0.81 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL18332397 | 0.79 | L3MBTL1 (0.48) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL20084038 | 0.78 | L3MBTL1 (0.39) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL2258320 | 0.74 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL9022132 | 0.73 | HSD17B10 (0.53) | CYP3A4ALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL10184964 | 0.72 | L3MBTL1 (0.59) | CYP3A4TSHRALDH1A1THRBHPGD | |
| SCHEMBL31623389 | 0.72 | L3MBTL1 (0.59) | CYP3A4TSHRALDH1A1THRBHPGD | |
| SCHEMBL13514315 | 0.71 | CYP19A1 (0.46) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL4817924 | 0.69 | CYP3A4 (0.47) | CYP3A4TSHRALDH1A1RECQLL3MBTL1 | |
| SCHEMBL4015170 | 0.69 | FSCN1 (0.54) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415641-B1 | Substituted glutaramic acids and derivatives | ROHM & HAAS (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |