Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18331702 | 0.81 | L3MBTL1 (0.36) | L3MBTL1CYP19A1CA2CA12CA1 | |
| SCHEMBL18332397 | 0.79 | L3MBTL1 (0.48) | L3MBTL1CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9370034 | 0.78 | CYP3A4 (0.45) | L3MBTL1CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6841374 | 0.74 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19CA2CA12 | |
| SCHEMBL30204314 | 0.73 | CYP19A1 (0.45) | L3MBTL1CYP19A1CYP3A4CA2CA12 | |
| SCHEMBL13514315 | 0.71 | CYP19A1 (0.46) | L3MBTL1CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3030207 | 0.67 | TDP1 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL12496190 | 0.67 | L3MBTL1 (0.62) | L3MBTL1CYP3A4CA2CA12CA1 | |
| Ethane SCHEMBL22412774 | 0.67 | CA2 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL6660474 | 0.67 | KMT2A (0.36) | KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |