Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.59 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 3/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4'-Methylenedianiline SCHEMBL5415789 | 0.80 | CYP3A4 (0.74) | ALDH1A1TDP1CYP3A4TSHRPTPRC | |
| Dichlon SCHEMBL45723 | 0.77 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| Dichlon SCHEMBL29360991 | 0.77 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| Dichlon SCHEMBL9751236 | 0.77 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| SCHEMBL9642148 | 0.76 | IDO1 (0.52) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| SCHEMBL16938308 | 0.75 | MEN1 (0.65) | IDO1ALDH1A1TDP1CYP3A4TSHR | |
| Dichlon SCHEMBL28269079 | 0.75 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| Dichlon SCHEMBL5077878 | 0.75 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| Dichlon SCHEMBL10794085 | 0.75 | IDO1 (0.94) | IDO1DNMT1DNMT3LDNMT3AALDH1A1 | |
| SCHEMBL12834662 | 0.74 | TBXAS1 (0.57) | ALDH1A1TDP1CYP3A4TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356499-A | Method for increasing fiber strength translation in composite pressure vessels using matrix resin formulations containing surface acting agents | THIOKOL CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |