Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293098 | 0.91 | ESR1 (0.54) | KDM4EALDH1A1CYP2C19HTR1AADRA2A | |
| SCHEMBL9370013 | 0.84 | TDP1 (0.61) | KDM4EALDH1A1L3MBTL1KMT2ATDP1 | |
| SCHEMBL3293101 | 0.84 | CYP4F2 (0.50) | KDM4EALDH1A1CYP2C19ADRA2ASLC6A2 | |
| SCHEMBL4789964 | 0.81 | CA2 (0.53) | KDM4EALDH1A1CYP2C19HTR1AADRA2A | |
| SCHEMBL5606900 | 0.79 | ESR1 (0.50) | KDM4EALDH1A1CYP2C19HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL28087587 | 0.78 | TDP1 (0.50) | KDM4EALDH1A1CYP2C19HTR1AADRA2A | |
| SCHEMBL17107198 | 0.77 | TDP1 (0.68) | KDM4EALDH1A1CYP2C19KMT2ATDP1 | |
| SCHEMBL7596354 | 0.76 | SLC7A5 (0.54) | SLC6A2TAAR1TDP1ESR1ESR2 | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL95254 | 0.76 | HDAC2 (0.53) | KDM4EALDH1A1CYP2C19KMT2ATDP1 | |
| SCHEMBL12431556 | 0.75 | ESR1 (0.45) | KDM4EALDH1A1CYP2C19HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207684-B1 | 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs | SQUIBB & SONS INC (US) | 1994-11-23 | — | — | EP | disclosed |
| US-4738978-A | ANTICOAGULANT, ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1988-04-19 | — | — | US | disclosed |
| US-4735962-A | ANTICOAGULANTS, BRONCHODILATORS | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4734424-A | ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734426-A | CARDIOVASCULAR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4663336-A | ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0207684-A2 | 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1987-01-07 | — | — | EP | disclosed |