Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658993 | 0.90 | CA2 (0.60) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL196524 | 0.82 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1KMT2ATDP1MAPK1 | |
| SCHEMBL9370231 | 0.81 | KDM4E (0.48) | CA2ABATIDO1ALDH1A1L3MBTL1 | |
| SCHEMBL4659000 | 0.78 | CA2 (0.52) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL27937110 | 0.78 | CA2 (0.55) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL16066069 | 0.78 | CA2 (0.59) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL26913876 | 0.76 | KMT2A (0.56) | CA2ALDH1A1L3MBTL1KDM4EKMT2A | |
| Tyrosine SCHEMBL1857842 | 0.76 | SLC7A5 (0.75) | ALDH1A1KDM4EADRA2AKMT2ATDP1 | |
| SCHEMBL31171268 | 0.76 | KMT2A (0.57) | CA2CAMK2AABATIDO1ALDH1A1 | |
| SCHEMBL27903659 | 0.75 | CA2 (0.61) | CA2CAMK2AFNTAFNTBABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |