Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678513 | 0.82 | TSHR (0.44) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL289488 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL17224645 | 0.71 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL9766503 | 0.71 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL3711104 | 0.70 | CES2 (0.36) | ALDH1A1TSHRTP53KMT2AMEN1 | |
| SCHEMBL9621651 | 0.69 | TSHR (0.42) | ALDH1A1TSHRTP53KMT2ALMNA | |
| SCHEMBL10471573 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53KMT2AHTT | |
| SCHEMBL20503396 | 0.68 | CYP4F2 (0.40) | ALDH1A1TSHRKMT2ALMNAHTT | |
| SCHEMBL8691775 | 0.67 | TSHR (0.40) | ALDH1A1TSHRTP53 | |
| SCHEMBL26939978 | 0.67 | TSHR (0.40) | ALDH1A1TSHRTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325730-B1 | Method for the preparation of O-carboxyarylimindazolinones | AMERICAN CYANAMID CO (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5103009-A | Method for the preparation of herbicidal intermediates | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5034532-A | Oxidation and treatment with a bromination agent | AMERICAN CYANAMID COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| US-4959476-A | CYCLIZATION, OXIDATION | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| US-4861887-A | CHEMICAL INTERMEDIATE FOR O-CARBOXYL IMIDAZOLINONE | AMERICAN CYANAMID COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| US-4576942-A | ANTIHISTAMINES, ASTHIMA | USV PHARMACEUTICAL CORP. (US) | 1986-03-18 | — | — | US | disclosed |