Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 10/20 | 0.42 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367906 | 0.85 | TAAR1 (0.47) | TAAR1NAMPTTERTFFAR2HRH4 | |
| Hydrochloric Acid SCHEMBL9372242 | 0.84 | TAAR1 (0.46) | TAAR1NAMPTTERTFFAR2HRH4 | |
| SCHEMBL9368208 | 0.81 | TAAR1 (0.46) | TAAR1NAMPTTERTFFAR2HRH4 | |
| SCHEMBL9368961 | 0.80 | NAMPT (0.44) | TAAR1NAMPTTERTHRH4AKT1 | |
| SCHEMBL9372244 | 0.78 | SIGMAR1 (0.46) | TAAR1NAMPT | |
| Hydrochloric Acid SCHEMBL9370769 | 0.77 | SIGMAR1 (0.45) | TAAR1NAMPT | |
| SCHEMBL9020747 | 0.76 | TAAR1 (0.45) | TAAR1NAMPTTERTHRH4TBXAS1 | |
| SCHEMBL9368868 | 0.75 | TAAR1 (0.48) | TAAR1NAMPTFFAR2TBXAS1 | |
| SCHEMBL21099034 | 0.73 | TERT (0.49) | TAAR1NAMPTTERTHRH4TBXAS1 | |
| SCHEMBL9367779 | 0.73 | TAAR1 (0.48) | TAAR1NAMPTTERTHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | claimed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |