Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.60 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366371 | 0.87 | ALOX5 (0.58) | ALOX5ADAM17MAOB | |
| SCHEMBL9366361 | 0.83 | ALOX5 (0.74) | ALOX5ADAM17 | |
| SCHEMBL9364971 | 0.83 | ALOX5 (0.63) | ALOX5ADAM17MAOB | |
| SCHEMBL9365123 | 0.82 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9365009 | 0.80 | ALOX5 (0.67) | ALOX5ADAM17 | |
| SCHEMBL9364733 | 0.78 | ALOX5 (0.60) | ALOX5ADAM17 | |
| SCHEMBL9365149 | 0.75 | ALOX5 (1.00) | ALOX5ADAM17 | |
| SCHEMBL9583811 | 0.75 | ALOX5 (0.66) | ALOX5ADAM17 | |
| SCHEMBL9740631 | 0.74 | ALOX5 (0.48) | ALOX5ADAM17MAOB | |
| SCHEMBL9022908 | 0.74 | ALOX5 (0.57) | ALOX5ADAM17MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375457-B1 | Cyclic ether derivatives | ICI PLC (GB) | 1994-03-16 | — | — | EP | disclosed |
| US-5219881-A | Enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0375457-A2 | Cyclic ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |